Our Team
Principal Investigator
Jun Qi, Ph.D.
Jun received his BS degree from Fudan University in China, obtained his Ph.D. in Chemistry from University of Michigan with Prof. William Roush in 2006, and completed his postdoctoral training at MIT with Prof. Mo Movassaghi in 2009. Both his Ph.D. and postdoctoral studies have been focused on the total synthesis of natural compounds and novel synthetic methodology development. After his postdoctoral training, he led the chemistry effort in Dr. James Bradner's laboratory on developing BET bromodomain inhibitor JQ1 and optimizing this chemistry probe to a human clinical candidate. His study focuses on the design and synthesis of small molecule inhibitors targeting the gene regulation pathway for cancer therapy; and on understanding the roles of epigenetic proteins in cancers.
Email
Jun received his BS degree from Fudan University in China, obtained his Ph.D. in Chemistry from University of Michigan with Prof. William Roush in 2006, and completed his postdoctoral training at MIT with Prof. Mo Movassaghi in 2009. Both his Ph.D. and postdoctoral studies have been focused on the total synthesis of natural compounds and novel synthetic methodology development. After his postdoctoral training, he led the chemistry effort in Dr. James Bradner's laboratory on developing BET bromodomain inhibitor JQ1 and optimizing this chemistry probe to a human clinical candidate. His study focuses on the design and synthesis of small molecule inhibitors targeting the gene regulation pathway for cancer therapy; and on understanding the roles of epigenetic proteins in cancers.
Postdoctoral Fellows
Lingling Dai, Ph.D.
Lingling completed a joint Ph.D. program from Harvard T.H. Chan School of Public Health and Central South University where she focused on immune-metabolic signaling crosstalk under physiological and pathological conditions. She joined the Qi lab in September 2017. Outside of lab she enjoys skiing and eating chocolate.
Ph.D. Harvard T.H. Chan School of Public Health and Central South University
B.S. Central South University
Email
Lingling completed a joint Ph.D. program from Harvard T.H. Chan School of Public Health and Central South University where she focused on immune-metabolic signaling crosstalk under physiological and pathological conditions. She joined the Qi lab in September 2017. Outside of lab she enjoys skiing and eating chocolate.
Ph.D. Harvard T.H. Chan School of Public Health and Central South University
B.S. Central South University
Xiaofeng Zhang, Ph.D.
Xiaofeng worked in Pharmaron, where he was trained in reaction route design/optimization, process development and manufacturing of various target molecules, such as Austedo. He then completed his Ph.D. in Organic Chemistry from UMass Boston with Prof. Wei Zhang, where he focused on organic synthesis of small molecule inhibitors, PROTACs, and fluorescent compounds. He joined the Qi lab in June 2019 and is interested in medicinal organic small molecule synthesis. Outside of lab, he enjoys swimming and traveling.
Ph.D. University of Massachusetts, Boston
M.S. Jilin University
B.S. Changchun Normal University
Email
Xiaofeng worked in Pharmaron, where he was trained in reaction route design/optimization, process development and manufacturing of various target molecules, such as Austedo. He then completed his Ph.D. in Organic Chemistry from UMass Boston with Prof. Wei Zhang, where he focused on organic synthesis of small molecule inhibitors, PROTACs, and fluorescent compounds. He joined the Qi lab in June 2019 and is interested in medicinal organic small molecule synthesis. Outside of lab, he enjoys swimming and traveling.
Ph.D. University of Massachusetts, Boston
M.S. Jilin University
B.S. Changchun Normal University
Tingjian Wang, M.D., Ph.D.
Tingjian is a certified neurosurgeon in China and is now a biology postdoc fellow in the Qi lab interested in using probes to understand biological mechanisms in cancer. He completed his M.D. & Ph.D. from Capital Medical University where he focused on the application of nanomaterials in neuro-oncology. He joined the Qi lab in August 2019 to discovery novel therapeutic strategy for brain tumor. Outside of the lab, he enjoys sports and photography.
M.D. & Ph.D. Capital Medical University, Beijing, China
M.M Central South University
B.S. Central South University
Email
Tingjian is a certified neurosurgeon in China and is now a biology postdoc fellow in the Qi lab interested in using probes to understand biological mechanisms in cancer. He completed his M.D. & Ph.D. from Capital Medical University where he focused on the application of nanomaterials in neuro-oncology. He joined the Qi lab in August 2019 to discovery novel therapeutic strategy for brain tumor. Outside of the lab, he enjoys sports and photography.
M.D. & Ph.D. Capital Medical University, Beijing, China
M.M Central South University
B.S. Central South University
Andrew P. Groves, M.D.
Andrew earned his B.A. in Chemistry and Mathematics from Northwestern University, and then went on to Washington University School of Medicine in St. Louis to complete his M.D. training. Andrew completed pediatric residency in the Boston Combined Residency Program (Boston Children’s Hospital/Boston Medical Center) in 2019. During residency, Andrew worked with Dr. Mariella Filbin on projects involving next-generation sequencing of pediatric brain tumors, as well as drug screening in Diffuse Intrinsic Pontine Glioma (DIPG) cell lines. He is currently a fellow in the Pediatric Hematology/Oncology Fellowship Program at Boston Children’s Hospital/Dana-Farber Cancer Institute. Andrew joined the Qi lab in July of 2020, and continues to be co-mentored by Mariella Filbin. His interests lie in the epigenetic mechanisms that drive and sustain pediatric brain tumor growth, and exploiting these mechanisms to develop better treatments. Outside of the lab he enjoys running, playing golf, and spending time with family.
M.D. Washington University School of Medicine in St. Louis
B.A. Northwestern University
Email
Andrew earned his B.A. in Chemistry and Mathematics from Northwestern University, and then went on to Washington University School of Medicine in St. Louis to complete his M.D. training. Andrew completed pediatric residency in the Boston Combined Residency Program (Boston Children’s Hospital/Boston Medical Center) in 2019. During residency, Andrew worked with Dr. Mariella Filbin on projects involving next-generation sequencing of pediatric brain tumors, as well as drug screening in Diffuse Intrinsic Pontine Glioma (DIPG) cell lines. He is currently a fellow in the Pediatric Hematology/Oncology Fellowship Program at Boston Children’s Hospital/Dana-Farber Cancer Institute. Andrew joined the Qi lab in July of 2020, and continues to be co-mentored by Mariella Filbin. His interests lie in the epigenetic mechanisms that drive and sustain pediatric brain tumor growth, and exploiting these mechanisms to develop better treatments. Outside of the lab he enjoys running, playing golf, and spending time with family.
M.D. Washington University School of Medicine in St. Louis
B.A. Northwestern University
Graduate Student
Paul M.C. Park (Ebert lab, Co-mentored by Dr. Qi)
Paul is from Takoma Park, Maryland, and attended college at Purdue University, where he worked for Professor Stephen Konieczny. His undergraduate research focused on defining key transcription factors related to pancreatic cancer. Paul worked in Qi lab as technician then computational biologist for three years. He was accepted by BBS program at HMS in 2019. Paul joined Dr. Ben Ebert lab in 2020 and co-mentored by Dr. Qi. Outside of lab, he enjoys hiking, playing soccer and basketball, and traveling.
B.S. Purdue University
Email
Paul is from Takoma Park, Maryland, and attended college at Purdue University, where he worked for Professor Stephen Konieczny. His undergraduate research focused on defining key transcription factors related to pancreatic cancer. Paul worked in Qi lab as technician then computational biologist for three years. He was accepted by BBS program at HMS in 2019. Paul joined Dr. Ben Ebert lab in 2020 and co-mentored by Dr. Qi. Outside of lab, he enjoys hiking, playing soccer and basketball, and traveling.
B.S. Purdue University
Research Technicians
Logan H. Sigua, Sr. Technician
Logan is from North Sutton, New Hampshire and earned his B.A. in Chemistry with a minor in Biology at Boston University. He worked in Professor Aaron Beeler's laboratory, where he investigated and developed selective functionalization of cycloheptatrienes to synthesize a small molecule library. Logan Joined the Qi lab in May 2019. Outside of lab, he enjoys playing flamenco guitar, tennis, video games, and listening to indie music.
B.A. Boston University
Logan is promoted to Sr. Technician with his outstanding performance in Sept. 2020.
Email
Logan is from North Sutton, New Hampshire and earned his B.A. in Chemistry with a minor in Biology at Boston University. He worked in Professor Aaron Beeler's laboratory, where he investigated and developed selective functionalization of cycloheptatrienes to synthesize a small molecule library. Logan Joined the Qi lab in May 2019. Outside of lab, he enjoys playing flamenco guitar, tennis, video games, and listening to indie music.
B.A. Boston University
Logan is promoted to Sr. Technician with his outstanding performance in Sept. 2020.
Ivy Yu Liang
Ivy is originally from Taipei, Taiwan and grew up in Shanghai. She earned my B.A in Chemistry at Boston University. Ivy worked in Professor Aaron Beeler’s Lab during her undergraduate study where she investigated synthesis and characterization of small molecule inhibitors for GIV-Galpha protein-protein interaction. Ivy joined the Qi lab in July 2020. In her free time, Ivy enjoys playing guitar, hiking, going to parks, and taking care of her plants.
B.A. Boston University
Email
Ivy is originally from Taipei, Taiwan and grew up in Shanghai. She earned my B.A in Chemistry at Boston University. Ivy worked in Professor Aaron Beeler’s Lab during her undergraduate study where she investigated synthesis and characterization of small molecule inhibitors for GIV-Galpha protein-protein interaction. Ivy joined the Qi lab in July 2020. In her free time, Ivy enjoys playing guitar, hiking, going to parks, and taking care of her plants.
B.A. Boston University
Priscilla Liow
Priscilla is from Columbia, Missouri and earned her B.S. in Chemistry with minors in Music and Mathematics at the Massachusetts Institute of Technology. At MIT, she worked in Dr. Stephen L. Buchwald's lab, where she developed transition metal catalysts to catalyze couplings and functionalizations of organic molecules. Priscilla joined the Qi lab in July 2020. In her free time, she enjoys taekwondo, cooking, and making music.
B.S. MIT
Email
Priscilla is from Columbia, Missouri and earned her B.S. in Chemistry with minors in Music and Mathematics at the Massachusetts Institute of Technology. At MIT, she worked in Dr. Stephen L. Buchwald's lab, where she developed transition metal catalysts to catalyze couplings and functionalizations of organic molecules. Priscilla joined the Qi lab in July 2020. In her free time, she enjoys taekwondo, cooking, and making music.
B.S. MIT
Post-Bacc Fellowship Trainee
Sang Vo
Sang Vo is from Boston, MA, and earned his B.S in Biochemistry at UMass Boston. He worked under Dr. Bela Torok generating a chemical library for a unique alpha-ketocarboxylic acid ester using heterogeneous catalytic hydrogenation. Sang was a summer intern at UMass Medical School generating and solving several co-crystal structures of a mutant HCV variant protease with several protease inhibitors that were potentially less susceptible to incur drug resistance. Moreover, Sang was also a summer intern at the Boston Children’s Hospital developing a new drug target for Cystic Fibrosis (CF) utilizing immortalized human bronchial epithelial cells and induced pluripotent stem cells derived from unique CF patients. Sang is selected for U54 Post-Bacc Fellowship from U Mass Boston, and joined the Qi lab in September 2020 to continue his research interest in Pharmacology and Chemical Biology. In his free time, Sang enjoys reading nonfiction literature and taking care of his cat, Chanel.
B.S. University of Massachusetts, Boston
Email
Sang Vo is from Boston, MA, and earned his B.S in Biochemistry at UMass Boston. He worked under Dr. Bela Torok generating a chemical library for a unique alpha-ketocarboxylic acid ester using heterogeneous catalytic hydrogenation. Sang was a summer intern at UMass Medical School generating and solving several co-crystal structures of a mutant HCV variant protease with several protease inhibitors that were potentially less susceptible to incur drug resistance. Moreover, Sang was also a summer intern at the Boston Children’s Hospital developing a new drug target for Cystic Fibrosis (CF) utilizing immortalized human bronchial epithelial cells and induced pluripotent stem cells derived from unique CF patients. Sang is selected for U54 Post-Bacc Fellowship from U Mass Boston, and joined the Qi lab in September 2020 to continue his research interest in Pharmacology and Chemical Biology. In his free time, Sang enjoys reading nonfiction literature and taking care of his cat, Chanel.
B.S. University of Massachusetts, Boston
Alumni
Adam Durbin, M.D., Ph.D. (08/2018-08/2020, Instructor, co-mentored with Drs. Tom Look and Kim Stegmaier)
Assistant Professor, St. Jude.
Deyao Li, Ph.D. (10/2018-06/2020, Postdoc Fellow)
Postdoc Fellow, MSKCC.
Virangika K. Wimalasena (06/2018-05/2020, Research Technician)
Graduate student at Johns Hopkins
Lei Wu, Ph.D. (08/2016 - 12/2018, Postdoc Fellow)
Senior Scientist at QL Regor
Mousheng Xu, Ph.D. (05/2016 - 11/2017, Bioinformatic Analyst II)
Senior Statistical Geneticist at Booz Allen Hamilton
Jennifer Perry, Ph.D. (01/2016 - 07/2017, Senior Scientist)
Associate Director for the Center of Pediatric Cancer Therapeutics at DFCI
Matthew Lawlor (01/2016 - 09/2017, Bioinformatic Analyst I)
Research Technician at MGH
Nana Kwaku Offei-Addo (08/2016 - 11/2017, Research Technician)
Research Associate at Generation Bio
Michael Xiang (2016, 2017, Summer Intern)
Undergraduate student at Johns Hopkins
Morgan Schwartz (2018, Summer Intern)
Undergraduate student at The University of Vermont
Paula Zoutine (2018, Intern)
Undergraduate student at Boston University
Adam Durbin, M.D., Ph.D. (08/2018-08/2020, Instructor, co-mentored with Drs. Tom Look and Kim Stegmaier)
Assistant Professor, St. Jude.
Deyao Li, Ph.D. (10/2018-06/2020, Postdoc Fellow)
Postdoc Fellow, MSKCC.
Virangika K. Wimalasena (06/2018-05/2020, Research Technician)
Graduate student at Johns Hopkins
Lei Wu, Ph.D. (08/2016 - 12/2018, Postdoc Fellow)
Senior Scientist at QL Regor
Mousheng Xu, Ph.D. (05/2016 - 11/2017, Bioinformatic Analyst II)
Senior Statistical Geneticist at Booz Allen Hamilton
Jennifer Perry, Ph.D. (01/2016 - 07/2017, Senior Scientist)
Associate Director for the Center of Pediatric Cancer Therapeutics at DFCI
Matthew Lawlor (01/2016 - 09/2017, Bioinformatic Analyst I)
Research Technician at MGH
Nana Kwaku Offei-Addo (08/2016 - 11/2017, Research Technician)
Research Associate at Generation Bio
Michael Xiang (2016, 2017, Summer Intern)
Undergraduate student at Johns Hopkins
Morgan Schwartz (2018, Summer Intern)
Undergraduate student at The University of Vermont
Paula Zoutine (2018, Intern)
Undergraduate student at Boston University