Our Team
Principal Investigator
Jun Qi, Ph.D.
Jun received his BS degree from Fudan University in China, obtained his Ph.D. in Chemistry from University of Michigan with Prof. William Roush in 2006, and completed his postdoctoral training at MIT with Prof. Mo Movassaghi in 2009. Both his Ph.D. and postdoctoral studies have been focused on the total synthesis of natural compounds and novel synthetic methodology development. After his postdoctoral training, he led the chemistry effort in Dr. James Bradner's laboratory on developing BET bromodomain inhibitor JQ1 and optimizing this chemistry probe to a human clinical candidate. His study focuses on the design and synthesis of small molecule inhibitors targeting the gene regulation pathway for cancer therapy; and on understanding the roles of epigenetic proteins in cancers.
Email
Jun received his BS degree from Fudan University in China, obtained his Ph.D. in Chemistry from University of Michigan with Prof. William Roush in 2006, and completed his postdoctoral training at MIT with Prof. Mo Movassaghi in 2009. Both his Ph.D. and postdoctoral studies have been focused on the total synthesis of natural compounds and novel synthetic methodology development. After his postdoctoral training, he led the chemistry effort in Dr. James Bradner's laboratory on developing BET bromodomain inhibitor JQ1 and optimizing this chemistry probe to a human clinical candidate. His study focuses on the design and synthesis of small molecule inhibitors targeting the gene regulation pathway for cancer therapy; and on understanding the roles of epigenetic proteins in cancers.
Postdoctoral Fellows
Tingjian Wang, M.D., Ph.D.
Tingjian is a certified neurosurgeon in China and is now a biology postdoc fellow in the Qi lab interested in using probes to understand biological mechanisms in cancer. He completed his M.D. & Ph.D. from Capital Medical University where he focused on the application of nanomaterials in neuro-oncology. He joined the Qi lab in August 2019 to discovery novel therapeutic strategy for brain tumor. Outside of the lab, he enjoys sports and photography.
M.D. & Ph.D. Capital Medical University, Beijing, China
M.M Central South University
B.S. Central South University
Email
Tingjian is a certified neurosurgeon in China and is now a biology postdoc fellow in the Qi lab interested in using probes to understand biological mechanisms in cancer. He completed his M.D. & Ph.D. from Capital Medical University where he focused on the application of nanomaterials in neuro-oncology. He joined the Qi lab in August 2019 to discovery novel therapeutic strategy for brain tumor. Outside of the lab, he enjoys sports and photography.
M.D. & Ph.D. Capital Medical University, Beijing, China
M.M Central South University
B.S. Central South University
Andrew P. Groves, M.D. (Co-mentored with Dr. Mariella Filbin)
Andrew earned his B.A. in Chemistry and Mathematics from Northwestern University, and then went on to Washington University School of Medicine in St. Louis to complete his M.D. training. Andrew completed pediatric residency in the Boston Combined Residency Program (Boston Children’s Hospital/Boston Medical Center) in 2019. During residency, Andrew worked with Dr. Mariella Filbin on projects involving next-generation sequencing of pediatric brain tumors, as well as drug screening in Diffuse Intrinsic Pontine Glioma (DIPG) cell lines. He is currently a fellow in the Pediatric Hematology/Oncology Fellowship Program at Boston Children’s Hospital/Dana-Farber Cancer Institute. Andrew joined the Qi lab in July of 2020, and continues to be co-mentored by Mariella Filbin. His interests lie in the epigenetic mechanisms that drive and sustain pediatric brain tumor growth, and exploiting these mechanisms to develop better treatments. Outside of the lab he enjoys running, playing golf, and spending time with family.
M.D. Washington University School of Medicine in St. Louis
B.A. Northwestern University
Email
Andrew earned his B.A. in Chemistry and Mathematics from Northwestern University, and then went on to Washington University School of Medicine in St. Louis to complete his M.D. training. Andrew completed pediatric residency in the Boston Combined Residency Program (Boston Children’s Hospital/Boston Medical Center) in 2019. During residency, Andrew worked with Dr. Mariella Filbin on projects involving next-generation sequencing of pediatric brain tumors, as well as drug screening in Diffuse Intrinsic Pontine Glioma (DIPG) cell lines. He is currently a fellow in the Pediatric Hematology/Oncology Fellowship Program at Boston Children’s Hospital/Dana-Farber Cancer Institute. Andrew joined the Qi lab in July of 2020, and continues to be co-mentored by Mariella Filbin. His interests lie in the epigenetic mechanisms that drive and sustain pediatric brain tumor growth, and exploiting these mechanisms to develop better treatments. Outside of the lab he enjoys running, playing golf, and spending time with family.
M.D. Washington University School of Medicine in St. Louis
B.A. Northwestern University
Michael Agius, Ph.D. (co-mentored with Dr. Irene Ghobrial)
Mike is originally from Livonia, Michigan and earned a B.S. in Chemistry and a B.S. in Biomedical Sciences from Grand Valley State University. He went on to earn his Ph.D. in Medicinal Chemistry from the University of Michigan under the supervision of Dr. Matthew Soellner. During his time at UM, Mike developed methods to elucidate conformational changes in the kinases c-Src and c-Abl, and further used this method to design and synthesize a large panel of ‘conformation-selective’ inhibitors against these kinases. He is currently a research fellow at DFCI where he is identifying new therapeutic opportunities in Multiple Myeloma. Mike joined the Qi lab in July 2021 and continues to be co-mentored by Irene Ghobrial. In his free time, he enjoys concerts, reality TV, and is part of a powerlifting club in Boston.
Ph.D. University of Michigan
B.S. Grand Valley State University
Mike is originally from Livonia, Michigan and earned a B.S. in Chemistry and a B.S. in Biomedical Sciences from Grand Valley State University. He went on to earn his Ph.D. in Medicinal Chemistry from the University of Michigan under the supervision of Dr. Matthew Soellner. During his time at UM, Mike developed methods to elucidate conformational changes in the kinases c-Src and c-Abl, and further used this method to design and synthesize a large panel of ‘conformation-selective’ inhibitors against these kinases. He is currently a research fellow at DFCI where he is identifying new therapeutic opportunities in Multiple Myeloma. Mike joined the Qi lab in July 2021 and continues to be co-mentored by Irene Ghobrial. In his free time, he enjoys concerts, reality TV, and is part of a powerlifting club in Boston.
Ph.D. University of Michigan
B.S. Grand Valley State University
Qi Liu, Ph.D.
Qi earned his B.S. in Chemistry from Jilin University in China, and then obtained his Ph.D. in Organic Chemistry from Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences under the supervision of Prof. Shengming Ma, where he focused on developing efficient methods for synthesis of propargylic amines and allenes from terminal alkynes. Then he moved to Fudan University as a research assistant in the laboratory of Prof. Shengming Ma, where he did some research on aerobic oxidation of light alkanes. He joined the Qi lab in April 2022. Outside of lab, he enjoys hiking and listening music.
Ph.D. Shanghai Institute of Organic Chemistry, Chinese Academy of Science
B.S. Jilin University
Qi earned his B.S. in Chemistry from Jilin University in China, and then obtained his Ph.D. in Organic Chemistry from Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences under the supervision of Prof. Shengming Ma, where he focused on developing efficient methods for synthesis of propargylic amines and allenes from terminal alkynes. Then he moved to Fudan University as a research assistant in the laboratory of Prof. Shengming Ma, where he did some research on aerobic oxidation of light alkanes. He joined the Qi lab in April 2022. Outside of lab, he enjoys hiking and listening music.
Ph.D. Shanghai Institute of Organic Chemistry, Chinese Academy of Science
B.S. Jilin University
Research Technicians
Logan H. Sigua, Sr. Technician
Logan is from North Sutton, New Hampshire and earned his B.A. in Chemistry with a minor in Biology at Boston University. He worked in Professor Aaron Beeler's laboratory, where he investigated and developed selective functionalization of cycloheptatrienes to synthesize a small molecule library. Logan Joined the Qi lab in May 2019. Outside of lab, he enjoys playing flamenco guitar, tennis, video games, and listening to indie music.
B.A. Boston University
Logan is promoted to Sr. Technician with his outstanding performance in Sept. 2020.
Email
Logan is from North Sutton, New Hampshire and earned his B.A. in Chemistry with a minor in Biology at Boston University. He worked in Professor Aaron Beeler's laboratory, where he investigated and developed selective functionalization of cycloheptatrienes to synthesize a small molecule library. Logan Joined the Qi lab in May 2019. Outside of lab, he enjoys playing flamenco guitar, tennis, video games, and listening to indie music.
B.A. Boston University
Logan is promoted to Sr. Technician with his outstanding performance in Sept. 2020.
Ivy Yu Liang
Ivy is originally from Taipei, Taiwan and grew up in Shanghai. She earned my B.A in Chemistry at Boston University. Ivy worked in Professor Aaron Beeler’s Lab during her undergraduate study where she investigated synthesis and characterization of small molecule inhibitors for GIV-Galpha protein-protein interaction. Ivy joined the Qi lab in July 2020. In her free time, Ivy enjoys playing guitar, hiking, going to parks, and taking care of her plants.
B.A. Boston University
Email
Ivy is originally from Taipei, Taiwan and grew up in Shanghai. She earned my B.A in Chemistry at Boston University. Ivy worked in Professor Aaron Beeler’s Lab during her undergraduate study where she investigated synthesis and characterization of small molecule inhibitors for GIV-Galpha protein-protein interaction. Ivy joined the Qi lab in July 2020. In her free time, Ivy enjoys playing guitar, hiking, going to parks, and taking care of her plants.
B.A. Boston University
Priscilla Liow
Priscilla is from Columbia, Missouri and earned her B.S. in Chemistry with minors in Music and Mathematics at the Massachusetts Institute of Technology. At MIT, she worked in Dr. Stephen L. Buchwald's lab, where she developed transition metal catalysts to catalyze couplings and functionalizations of organic molecules. Priscilla joined the Qi lab in July 2020. In her free time, she enjoys taekwondo, cooking, and making music.
B.S. MIT
Email
Priscilla is from Columbia, Missouri and earned her B.S. in Chemistry with minors in Music and Mathematics at the Massachusetts Institute of Technology. At MIT, she worked in Dr. Stephen L. Buchwald's lab, where she developed transition metal catalysts to catalyze couplings and functionalizations of organic molecules. Priscilla joined the Qi lab in July 2020. In her free time, she enjoys taekwondo, cooking, and making music.
B.S. MIT
Michelle Wang
Michelle is from Melville, New York and earned her B.S.E. in Biomedical Engineering from Duke University. After graduating from Duke, Michelle worked in Dr. Jianguo Tao’s laboratory at the H. Lee Moffitt Cancer Center & Research Institute for 3 years. She combined biological and biochemical benchwork with next-generation sequencing analysis to study drug resistance mechanisms in lymphomas, including those against MCL-1 inhibitors, CDK inhibitors, clinically used BTK inhibitor Ibrutinib, and CAR T-cell therapy. Michelle joined the Qi Lab in June 2021. Outside of the lab, she enjoys hiking, reading, and spending time outside.
B.S. Duke University
Michelle is from Melville, New York and earned her B.S.E. in Biomedical Engineering from Duke University. After graduating from Duke, Michelle worked in Dr. Jianguo Tao’s laboratory at the H. Lee Moffitt Cancer Center & Research Institute for 3 years. She combined biological and biochemical benchwork with next-generation sequencing analysis to study drug resistance mechanisms in lymphomas, including those against MCL-1 inhibitors, CDK inhibitors, clinically used BTK inhibitor Ibrutinib, and CAR T-cell therapy. Michelle joined the Qi Lab in June 2021. Outside of the lab, she enjoys hiking, reading, and spending time outside.
B.S. Duke University
Alumni
Xiaofeng Zhang, PhD. (08/2019-01/2022, Postdoctoral Fellow)
Senior Scientist at Cerevel Pharmaceutics.
Lingling Dai, PhD. (11/2017-08/2021, Postdoctoral Fellow)
Senior Scientist at AstraZeneca
Sang Vo, (09/2020-03/2021, Post-Bacc. Fellow U Mass Boston)
University of Minnesota, MD/PhD program
Adam Durbin, M.D., Ph.D. (08/2018-08/2020, Instructor, co-mentored with Drs. Tom Look and Kim Stegmaier)
Assistant Professor, St. Jude.
Deyao Li, Ph.D. (10/2018-06/2020, Postdoc Fellow)
Postdoc Fellow, MSKCC.
Virangika K. Wimalasena (06/2018-05/2020, Research Technician)
Graduate student at Johns Hopkins
Paul MC Park (10/2016-07/2019, Research Techinician)
Graduate Student at Harvard Medical School
Lei Wu, Ph.D. (08/2016 - 12/2018, Postdoc Fellow)
Senior Scientist at QL Regor
Mousheng Xu, Ph.D. (05/2016 - 11/2017, Bioinformatic Analyst II)
Senior Statistical Geneticist at Booz Allen Hamilton
Jennifer Perry, Ph.D. (01/2016 - 07/2017, Senior Scientist)
Associate Director for the Center of Pediatric Cancer Therapeutics at DFCI
Matthew Lawlor (01/2016 - 09/2017, Bioinformatic Analyst I)
Research Technician at MGH
Nana Kwaku Offei-Addo (08/2016 - 11/2017, Research Technician)
Research Associate at Generation Bio
Michael Xiang (2016, 2017, Summer Intern)
Undergraduate student at Johns Hopkins
Morgan Schwartz (2018, Summer Intern)
Undergraduate student at The University of Vermont
Paula Zoutine (2018, Intern)
Undergraduate student at Boston University
Xiaofeng Zhang, PhD. (08/2019-01/2022, Postdoctoral Fellow)
Senior Scientist at Cerevel Pharmaceutics.
Lingling Dai, PhD. (11/2017-08/2021, Postdoctoral Fellow)
Senior Scientist at AstraZeneca
Sang Vo, (09/2020-03/2021, Post-Bacc. Fellow U Mass Boston)
University of Minnesota, MD/PhD program
Adam Durbin, M.D., Ph.D. (08/2018-08/2020, Instructor, co-mentored with Drs. Tom Look and Kim Stegmaier)
Assistant Professor, St. Jude.
Deyao Li, Ph.D. (10/2018-06/2020, Postdoc Fellow)
Postdoc Fellow, MSKCC.
Virangika K. Wimalasena (06/2018-05/2020, Research Technician)
Graduate student at Johns Hopkins
Paul MC Park (10/2016-07/2019, Research Techinician)
Graduate Student at Harvard Medical School
Lei Wu, Ph.D. (08/2016 - 12/2018, Postdoc Fellow)
Senior Scientist at QL Regor
Mousheng Xu, Ph.D. (05/2016 - 11/2017, Bioinformatic Analyst II)
Senior Statistical Geneticist at Booz Allen Hamilton
Jennifer Perry, Ph.D. (01/2016 - 07/2017, Senior Scientist)
Associate Director for the Center of Pediatric Cancer Therapeutics at DFCI
Matthew Lawlor (01/2016 - 09/2017, Bioinformatic Analyst I)
Research Technician at MGH
Nana Kwaku Offei-Addo (08/2016 - 11/2017, Research Technician)
Research Associate at Generation Bio
Michael Xiang (2016, 2017, Summer Intern)
Undergraduate student at Johns Hopkins
Morgan Schwartz (2018, Summer Intern)
Undergraduate student at The University of Vermont
Paula Zoutine (2018, Intern)
Undergraduate student at Boston University